Craig M. Crews : rechercher sur Z-Library

Benjamin H.B. Kwok, Brian Koh, MacKevin I. Ndubuisi, Mikael Elofsson, Craig M. Crews

Année:

2008

Langue:

english

Fichier:

PDF, 399 KB

english, 2008

The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase

Journal:

Ny Sin, Lihao Meng, Margaret Q. W. Wang, James J. Wen, William G. Bornmann and Craig M. Crews

Année:

2001

Langue:

english

Fichier:

PDF, 377 KB

english, 2001

The Anti-Angiogenic Agent Fumagillin Covalently Binds and Inhibits the Methionine Aminopeptidase, MetAP-2

Journal:

Proceedings of the National Academy of Sciences

Année:

1997

Langue:

english

Fichier:

PDF, 919 KB

english, 1997

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Lu, Jing, Qian, Yimin, Altieri, Martha, Dong, Hanqing, Wang, Jing, Raina, Kanak, Hines, John, Winkler, James D., Crew, Andrew P., Coleman, Kevin, Crews, Craig M.

Journal:

Cromm, Philipp M., Crews, Craig M.

Année:

2015

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2015

Targeted Protein Degradation: from Chemical Biology to Drug Discovery

Journal:

Cell Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 2.70 MB

english, 2017

Assessing Different E3 Ligases for Small Molecule-induced Protein Ubiquitination and Degradation

Ottis, Philipp, Toure, Momar, Cromm, Philipp M., Ko, Eunhwa, Gustafson, Jeffrey L., Crews, Craig M

Journal:

ACS Chemical Biology

Année:

2017

Langue:

english

Fichier:

PDF, 1.95 MB

english, 2017

Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure Degradation Relationships

Burslem, George M, Ottis, Philipp, Jaime-Figueroa, Saul, Morgan, Alicia, Cromm, Philipp, Toure, Momar, Crews, Craig

Journal:

ChemMedChem

Année:

2018

Langue:

english

Fichier:

PDF, 1.53 MB

english, 2018

Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

Serebrenik, Yevgeniy V., Hellerschmied, Doris, Toure, Momar, López-Giráldez, Francesc, Brookner, Dennis, Crews, Craig M., Spang, Anne

Journal:

Molecular Biology of the Cell

Année:

2018

Langue:

english

Fichier:

PDF, 4.95 MB

english, 2018

Enhancing Anti-Proliferative Activity and Selectivity of a FLT-3 Inhibitor by PROTAC Conversion

Burslem, George M, Song, Jayoung, Chen, Xin, Hines, John, Crews, Craig M

Journal:

Journal of the American Chemical Society

Année:

2018

Langue:

english

Fichier:

PDF, 510 KB

english, 2018

Addressing Kinase-Independent Functions of Fak via PROTAC-mediated Degradation

Cromm, Philipp M., Samarasinghe, Kusal, Hines, John, Crews, Craig M

Journal:

Journal of the American Chemical Society

Année:

2018

Langue:

english

Fichier:

PDF, 964 KB

english, 2018

Targeted protein degradation: expanding the toolbox

Schapira, Matthieu, Calabrese, Matthew F., Bullock, Alex N., Crews, Craig M.

Journal:

Nature Reviews Drug Discovery

Année:

2019

Langue:

english

Fichier:

PDF, 2.87 MB

english, 2019

Simplified Synthetic TMC-95A/B Analogues Retain the Potency of Proteasome Inhibitory Activity

Zhi-Qiang Yang, Benjamin H. B. Kwok, Songnian Lin, Michael A. Koldobskiy, Craig M. Crews, Samuel J. Danishefsky

Journal:

John S. Schneekloth Jr., Craig M. Crews

Année:

2003

Langue:

english

Fichier:

PDF, 105 KB

english, 2003

Chemical Approaches to Controlling Intracellular Protein Degradation

Journal:

Peter C. Gareiss, Ashley R. Schneekloth, Michael J. Salcius, Seung-Yong Seo, Craig M. Crews

Année:

2005

Langue:

english

Fichier:

PDF, 198 KB

english, 2005

Identification and Characterization of a Peptidic Ligand for Ras

Journal:

Dr. Timothy W. Corson, Dr. Hüseyin Cavga, Dr. Nicholas Aberle, Prof. Craig M. Crews

Année:

2010

Langue:

english

Fichier:

PDF, 319 KB

english, 2010

Triptolide Directly Inhibits dCTP Pyrophosphatase

Journal:

Dr. Hyun Seop Tae, Dr. Thomas B. Sundberg, Dr. Taavi K. Neklesa, Devin J. Noblin, Dr. Jeffrey L. Gustafson, Dr. Anke G. Roth, Kanak Raina, Prof. Craig M. Crews

Année:

2011

Langue:

english

Fichier:

PDF, 388 KB

english, 2011

Identification of Hydrophobic Tags for the Degradation of Stabilized Proteins

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 461 KB

english, 2012

ChemInform Abstract: Total Synthesis of the Potent Proteasome Inhibitor Epoxomicin: A Useful Tool for Understanding Proteasome Biology.

Ny Sin, Kyung Bo Kim, Mikael Elofsson, Lihao Meng, Hak Auth, Benjamin H. B. Kwok, Craig M. Crews

Journal:

Année:

1999

Fichier:

PDF, 28 KB

1999

ChemInform Abstract: Efficient Stereoselective Syntheses of Isopanepoxydone and Panepoxydone: A Reassignment of Relative Configuration.

J. Brad Shotwell, Shaojing Hu, Eva Medina, Megumi Abe, Roger Cole, Craig M. Crews, John L. Wood

Journal:

Jayhyuk Myung, Kyung Bo Kim, Craig M. Crews

Année:

2001

Fichier:

PDF, 27 KB

2001

ChemInform Abstract: The Ubiquitin-Proteasome Pathway and Proteasome Inhibitors

Journal:

Année:

2001

Fichier:

PDF, 24 KB

2001

Total Synthesis of Luminacin D.

J. Brad Shotwell, Evan S. Krygowski, John Hines, Brian Koh, Elliott W. D. Huntsman, Hui Won Choi, John S. Schneekloth Jr., John L. Wood, Craig M. Crews

Journal:

Année:

2003

Fichier:

PDF, 83 KB

2003

Inhibitors of NF-ϰB Signaling: Design and Synthesis of a Biotinylated Isopanepoxydone Affinity Reagent.

J. Brad Shotwell, Brian Koh, Hui Won Choi, John L. Wood, Craig M. Crews

Journal:

Songnian Lin, Zhi-Qiang Yang, Benjamin H. B. Kwok, Michael Koldobskiy, Craig M. Crews, Samuel J. Danishefsky

Année:

2003

Fichier:

PDF, 158 KB

2003

Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z-Enamides. Some Preliminary Findings as to SAR.

Journal:

Leslie N. Aldrich, Sydney L. Stoops, Brenda C. Crews, Lawrence J. Marnett, Craig W. Lindsley

Année:

2004

Fichier:

PDF, 21 KB

2004

ChemInform Abstract: Total Synthesis and Biological Evaluation of Tambjamine K and a Library of Unnatural Analogues.

Journal:

Leah J. Campbell, Edna C. Suárez-Castillo, Humberto Ortiz-Zuazaga, Dunja Knapp, Elly M. Tanaka, Craig M. Crews

Année:

2011

Fichier:

PDF, 30 KB

2011

Gene expression profile of the regeneration epithelium during axolotl limb regeneration

Journal:

Developmental Dynamics

Année:

2011

Langue:

english

Fichier:

PDF, 2.61 MB

english, 2011

Construction of Highly Substituted Stereodefined Dienes by Cross-Coupling of α-Allenic Acetates

John S. Schneekloth Jr., Mathieu Pucheault, Craig M. Crews

Journal:

European Journal of Organic Chemistry

Année:

2007

Langue:

english

Fichier:

PDF, 148 KB

english, 2007

Temperature-dependent sex determination in the leopard gecko, Eublepharis macularius

Brian E. Viets, Alan Tousignant, Michael A. Ewert, Craig E. Nelson, David Crews

Journal:

Journal of Experimental Zoology Part A Ecological Genetics and Physiology

Année:

1993

Langue:

english

Fichier:

PDF, 507 KB

english, 1993

The ubiquitin-proteasome pathway and proteasome inhibitors

Jayhyuk Myung, Kyung Bo Kim, Craig M. Crews

Journal:

Medicinal Research Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 513 KB

english, 2001

Unexpected stereochemical tolerance for the biological activity of tyroscherin

Hyun Seop Tae, John Hines, Ashley R. Schneekloth, Craig M. Crews

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 518 KB

english, 2011

Developing microcolin A analogs as biological probes

Amit K. Mandal, John Hines, Kouji Kuramochi, Craig M. Crews

Journal:

John S. Schneekloth Jr., John L. Sanders, John Hines, Craig M. Crews

Année:

2005

Langue:

english

Fichier:

PDF, 588 KB

english, 2005

Neurotrophic peptide aldehydes: Solid phase synthesis of fellutamide B and a simplified analog

Journal:

Leslie N. Aldrich, Sydney L. Stoops, Brenda C. Crews, Lawrence J. Marnett, Craig W. Lindsley

Année:

2006

Langue:

english

Fichier:

PDF, 157 KB

english, 2006

Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs

Journal:

Current Opinion in Chemical Biology

Année:

2010

Langue:

english

Fichier:

PDF, 718 KB

english, 2010

Feeding the machine: mechanisms of proteasome-catalyzed degradation of ubiquitinated proteins

Craig M Crews

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 729 KB

english, 2003

Studies on Calcium Dependence Reveal Multiple Modes of Action for Triptolide

Stephanie J. Leuenroth, Craig M. Crews

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 482 KB

english, 2005

A Chemical and Genetic Approach to the Mode of Action of Fumagillin

Yi Zhang, Jing Ruey Yeh, Andrew Mara, Rong Ju, John F. Hines, Pasquale Cirone, Hilary L. Griesbach, Igor Schneider, Diane C. Slusarski, Scott A. Holley, Craig M. Crews

Journal:

John Hines, Michael Groll, Margaret Fahnestock, Craig M. Crews

Année:

2006

Langue:

english

Fichier:

PDF, 458 KB

english, 2006

Proteasome Inhibition by Fellutamide B Induces Nerve Growth Factor Synthesis

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2008

Something Old, Something New

Craig Crews, Michael Famulok, Kevan Shokat, Wolfgang Wohlleben, Milka Kostic

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 39 KB

english, 2009

Targeting the Undruggable Proteome: The Small Molecules of My Dreams

Craig M. Crews

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 315 KB

english, 2010

Chemistry & Biology Editors Announce Changes to the Editorial Team

Craig Crews, Kevan Shokat, Wolfgang Wohlleben, Milka Kostic

Journal: